Nicotine Stomatitis: What Is The Relation in Between?


by Christina Matthews

Updated: August 7, 2020

the relation between Nicotine and Stomatitis

What Is Stomatitis?

Stomatitis is an inflammation of the inside part of the mouth. It can affect all parts of the mouth, lips, cheeks,  gums, tongue and the palates. Stomatitis is characterized by redness and swelling on the affected areas inside the mouth. It can cause discomfort and pain and in some severe cases can cause bleeding.

The three most common types of stomatitis are:

  • Herpes stomatitis (cold sores)
  • Aphthous stomatitis (canker sores)
  • Nicotine stomatitis

How Are Nicotine And Stomatitis Related?

Nicotine and stomatitis are related because smoking can cause a condition known as nicotine stomatitis. Nicotine stomatitis is different from other forms of stomatitis since it mostly affects just the upper palate of the mouth and is caused primarily by heavy smoking.

The other kinds of stomatitis have different causes. Herpes stomatitis (cold sores) is caused by the herpes simplex 1 virus (HSV-1) and aphthous stomatitis (canker sores) has many different causes, which vary from poor hygiene to allergic reactions.


The causes of nicotine stomatitis are:

  • Chronic pipe, cigar and cigarette smoking
  • Reverse cigarette smoking
  • High concentrations of heat hitting the roof of your mouth
  • Chemical irritants
  • Chronic drinking of hot liquids combined with smoking
You get nicotine stomatitis from the heat and chemicals in a burning tobacco product. The heat from a tobacco product causes a reaction in the upper part of the mouth that makes it more vulnerable to chemical irritants in tobacco smoke, like nicotine. Pipe and cigar smokers are the most likely people to get nicotine stomatitis.

Risk Factors

You are most at risk of developing nicotine stomatitis if you:

  • Are a longtime smoker of pipes and cigars
  • Are male
  • Reverse smoke (put the lit end in your mouth)
Nicotine stomatitis is an uncommon condition. It used to be common when smoking pipes was still a popular way to smoke tobacco.  Since smoking trends have changed and more people just smoke cigarettes or use e-cigarettes with vape juices and e-liquids inside. One study found that 29.6% of all smokers had nicotine stomatitis but 60% of pipe smokers had nicotine stomatitis.

Signs of Nicotine Stomatitis

Most cases of nicotine stomatitis include:

  • Gray or white patches on the skin of the palate
  • Red or white dots begin to appear when the salivary glands are inflamed
  • Severe cases include a “dried lake-bed” look, which is caused by fissures in the mucous membrane

FAQ: Nicotine Stomatitis

  • Are There Other Ways I Can Get Nicotine Stomatitis?

    Other than smoking tobacco products, there are no other ways to get nicotine stomatitis. Nicotine stomatitis does not occur from taking other forms of nicotine, like chewing gums and patches or e-cigarettes. The combination of heat and smoke that is unique to smoking tobacco products like pipes and cigars are the main factors that cause nicotine stomatitis.

  • Is Nicotine Stomatitis Dangerous?

    Nicotine stomatitis is not dangerous. Some smokers do not even know that they have nicotine stomatitis. Aside from the inflammation and the lesions it causes, there are no symptoms associated with nicotine stomatitis. It does not cause pain or lead to any other medical conditions. It is, at worst, mildly irritating.

  • Does Nicotine Stomatitis Cause Cancer?

    Nicotine stomatitis does not cause cancer, neither is it a type of cancer. However, in cases of reverse smoking, where the lit end of a cigarette is put into the mouth (which is a common practice in Southeast Asia and China) the lesions that appear can sometimes carry the risk of transforming into cancer.


The best way to prevent getting nicotine stomatitis is to stop smoking. Other ways to prevent nicotine stomatitis:

  1. The majority of cases that involve nicotine stomatitis come from people who are regular pipe or cigar smokers, so you might consider smoking cigarettes instead or trying some form of nicotine replacement therapy or even using vapes, for a while.
  2. If you are a reverse cigarette smoker, nicotine stomatitis could lead to more serious afflictions, so try smoking cigarettes from the filter.
  3. Some people who wear dentures and smoke do not develop nicotine stomatitis under the area covered by their dentures, but they do develop it in the parts of the mouth not covered by their dentures.


If you are showing signs of nicotine stomatitis, don’t panic. Nicotine stomatitis is not a serious or life-threatening affliction. You should stop smoking for a few weeks and the lesions on the upper palate of your mouth will disappear, even if you have had nicotine stomatitis for a long time. If you have stopped smoking but the lesions are still present, you should go see a doctor, since that would be a sign of something more serious.


There are a lot of dangers associated with smoking: strokes, heart attacks, cancer. Nicotine stomatitis is a less serious condition that will cause mostly discomfort but it is not life-threatening. If you are worried about developing nicotine stomatitis then you should check the inside of your mouth regularly, not only as a way to detect nicotine stomatitis but to check if you have any other major conditions as well.

Published: September 7, 2017Updated: August 7, 2020

Christina Matthews

I love the written word, and in my career as a journalist, I strive to provide the facts about everything I write about. There are too many false and alarmist stories out there about life and vaping mainly. My mission is to make e-cigarettes less scary to people with informative articles and extensive research on not only the possible evils of cigarettes and Big Tobacco, but the objective side of e-cigs.


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