Most popular
Empe CBD Vape Juice
10/10 icon-question
  • American made CBD liquid
  • Natural CBD isolate
  • Food grade ingredients

Empe has several e-liquid flavors: Wild Cherry, Gorilla Og, Tropical, Watermelon Taffy, and Blue Dream. Wild Cherry is the most popular i...

Koi CBD E-Liquid
Koi CBD E-Liquid
  • Food grade ingredients
  • Cloud e-liquid 9.4/10
  • 100% CBD, 0% THC
CBD Genesis E-Liquid
CBD Genesis E-Liquid
  • Helps with relaxation, anxiety, sleep, and stress
  • Varying strengths of 100mg, 350mg, 550mg, 1000mg, 1500mg and 2000mg
  • 0% PG

How to Choose the Best CBD Vape Oil

These products are available in various brands both – local and foreign. Every brand consistently insists on having the best e-juices with CBD.

The best way to get quality CBD oils is by reading the CBD e-juice review below. A genuine CBD vape oil review reveals pros and cons to help a customer get accurate information that enhances an apprised purchasing process.

Best CBD E-Liquids On the Market

#1 Empe CBD Vape Juice

0.8 oz
100% Natural Cannabidiol (CBD) Isolate, Food Grade Vegetable Glycerin, Propylene Glycol, Natural & Artificial Flavorings
Flavor quality
Vapor production
Throat hit


  • The company is located in the United States
  • Liquids are lab tested
  • Five flavors are available
  • Decently priced
  • Zero THC


  • Only 350 mg bottles are available

Empe has several e-liquid flavors: Wild Cherry, Gorilla Og, Tropical, Watermelon Taffy, and Blue Dream. Wild Cherry is the most popular in this group. Vapers will not only enjoy the health benefits of CBD by choosing this brand, such as pain relief, but they can enjoy great flavors, too.

Empe uses 100 percent natural CBD isolate and food-grade vegetable glycerine and propylene glycol. The e-juice has natural and artificial flavorings. Their products are lab tested to ensure that only the highest quality ingredients are used. Customers will not ingest THC, harmful chemicals, or dangerous metals.

Empe makes all of its products in the United States using locally harvested hemp. Customers of this company can trust that these liquids are made with great care by detail-oriented employees. CBD users will not only be buying high-quality juice, but their purchase will help support American jobs and industry.

#2 Koi CBD E-Liquid

Red, Gold, White, Green, Blue, Pink, Tropical Popsicle, Raspberry Iced Tea, Fuji Apple
Bottle size:
Flavor quality
Vapor production
Throat hit


  • 100% CBD, 0% THC
  • Available in up to six flavors, including Red, Gold, White, Jade, Blue, and Pink
  • Varying concentrations of 1000 mg cbd vape liquid, 500mg, 250mg and 100mg
  • Food grade ingredients
  • Cloud e-liquid 9.4/10


  • May feel harsh on the throat for non-smokers
  • Some flavors may taste a bit sour
  • Order a bottle today for a unique vaping experience!

Koi CBD is the accurate measure of an ideal e-liquid with CBD. It comes in a wide selection of fresh and elevating flavors. This product is designed for vape devices and as a tincture.

Koi CBD e-liquid is one of the most affordable CBD products in the current market. It offers customers higher value for its money in every bottle.

This production is reviewed as one of the best e-liquid for clouds. This CBD oil e-liquid made with pure CBD that has no traces of THC. Its ingredients include natural CBD isolate, food-grade VG, PG, natural and artificial flavors.

#3 CBD Genesis E-Liquid

Bottle size:
Flavor quality
Vapor production
Throat hit


  • Helps with relaxation, anxiety, sleep, and stress
  • Varying strengths of 100mg, 350mg, 550mg, 1000mg, 1500mg and 2000mg
  • 0% PG


  • The taste might change if kept for too long
  • May sometimes require thinning
  • Order online for an unusual vaping twist of smooth flavors!

CBD Genesis is an e-liquid that contains a full-spectrum hemp oil perfect for vaping or oral use. The e-liquid is PG-free so that it can vape on its own. Users can also add it to their favorite e-juice to get all the stress-relieving effects of hemp oil.

The cannabidiol content options range from 100mg to 2000mg. Genesis comes in 30ml bottles with a dropper inside to let users take the liquid under the tongue. They recommended 1-3 drops at first to feel the effects.

#4 CBD Oil Vape Additives 4 Pack

vd-coupon__gift10% OFF
Today’s exclusive offer
tea-like flavor profile of the natural hemp plan
60mg, 120mg, 300mg and 500mg
Bottle size:
Flavor quality
Vapor production
Throat hit


  • Made from all-natural, organic hemp plants
  • CO2 extraction ensures the purest oil possible
  • Perfectly blended with PG/VG for great cloud production


  • Separates quickly
  • Need to determine right strength to be effective

CBDfx vape oil additives are perfect for adding to vape juices, vaped on their own, or taken orally. The 4-pack comes with four, 10ml bottles of varying strengths, from 60mg to 500mg.

The oil in each juice comes from all-organic hemp plants and is made in the USA through CO2 extraction. C02 extraction means the oil has no harmful chemicals in it.

Each bottle contains a homemade blend of PG/VG and hemp oil, so it is ready to vape on its own. Users can also add them to their favorite e-juice so they can dose some cannabidiol.

#5 Driven CBD E-Juice

CBD strength:
250 - 1000mg
Bottle size:
Propylene glycol, Vegetable glycerine, Cannabidiol (CBD) Isolate, Natural and Artificial flavor concentrate
Flavor quality
Vapor production
Throat hit

Driven uses a combination of natural and artificial flavor concentrates to create an amazing blueberry candy flavor. Beneath the sweetness is the notes of sour candy, which is added just enough to make it perfect.

The result is a fantastic and sweet and sour blueberry candy blend that works on all kinds of vapes. The biggest benefit of using this liquid is that it uses highly concentrated CBD isolate, making it excellent for alleviating the symptoms of stress, pain, and anxiety. Choose 250 to 1,000 mg CBD options. The juice comes in 30 ml bottles.

Best CBD Vape Oil & CBD Juice

Category CBD Vape Juice Price
Best CBD Vape Liquid of 2022 Empe CBD Vape Juice $29.99
Concentrated CBD Vape E-juice CBD Genesis E-Liquid $14.99
CBD Oil Pack CBDfx Oil Vape Additives 4 Pack ~$144 (with a 10% off coupon)
Best VG/PG CBD Vape E-juice CBD Vape Juices By CBDfx $35.99 (with a 10% off coupon)
Best Natural CBD Vape Oil Select CBD Drops $69.99
Best CBD Vape Juice for Sub-Ohm Tanks Driven CBD E-Juice $28.99

What is CBD Oil

CBD Oil – short for Cannabidiol oil – is derived from the male cannabis plant, also known as hemp. These liquids are legal unlike its counterpart THC (Tetrahydrocannabinol), the chemical compound found in cannabis responsible for a euphoric high. CBD oil may or may not contain traces of THC.

CBD hemp oil is the oil that has been used for tinctures, but the term has floated over to vaping community. You can take these oil orally; however, most oils produced for oral consumption are not suitable for vaping.


CBD e-liquids refer to the fluids in vaporizers, e-cigarettes, or CBD vape pens. Also called vape oils, it is considered a more convenient option for individuals to consume cannabidiol. Looking for the best vape juice for clouds people need to check out CBD vape oil effects and find the best option.

CBD flavored e-liquids are the example of the latest developments in the vaping world. The first step in search of CBD e-liquids in the current market is understanding the source, properties, and work principles.

Properties of a-true-CBD-E-Juice-image


Despite the popularity of consuming flavored CBD e-liquids, a few people understand how it works. The internal performance is a thing to look at choosing the best CBD e-juice cig.

Whenever e-juice is vaporized or inhaled, it gets into the lungs, from where it spreads into the bloodstream. Even smaller amounts of cannabidiol produce the beneficial effects that come with oral use.

Since the process of vaping does not entail passing cannabidiol through the gut, it usually takes a relatively shorter period for the compound to become active in the body.

In fact, vaporized CBD e-liquids unleash their effects on users much faster than consuming it via other methods. While CBD vape oil and juice effects vary, the product is considered recreational.

Thus, CBD vape oil is mainly used to help with balancing the body’s endocannabinoid system. Cannabidiol producers claim potential health benefits.


Marijuana CBD Vs THC Poster with Scientific Formula
Shutterstock / PRO Stock Professional

Cannabidiol and Tetrahydrocannabinol are the essential chemical compounds found in the cannabis plant. While both interact with the body’s endocannabinoid system, each has unique natural effects on the human body.

Studies have established that THC is the primary compound responsible for the high that people get from consuming cannabis.

Nonetheless, research has indicated that e-liquid cannabidiol can assist in balancing the effects of THC while potentially providing medical and symptom relief benefits.

A clear distinction between these compounds is in some of the critical psychological and physical effects, potential medical uses, and the legality of the two cannabinoids.


While THC has been proven to generate ‘highness,’’ cannabidiol has non-psychoactive benefits.
THC is the chemical compound known to generate the euphoric or high sensation that achieves by cannabis use.

That’s because THC activates the CB1 receptors in the brain. As a result, appears alteration of some organs function. Precisely this exchange of the brain’s functionality creates a high sensation.

On the other hand, CBD is the exact opposite of THC since it does not bind to the CB1 receptors. The implication is that even after using vast amounts of CBD vape oil, it is tough for a consumer to get high.

What’s more, this chemical compound significantly suppresses the effects of substances that bond with CB1 reactors like THC.


Since THC interacts with CB1 receptors directly, it stimulates the body in specific ways. Most of the material effects of THC are transient changes that appear after taking substances containing this compound.

While the physical effects of THC may vary from one individual to another, there are general effects for most consumers.


These effects also resemble in the form of increased heart rate, dry mouth, and red eyes. But, most of these effects are usually short-lived.

Unlike THC, cannabidiol has an indirect interaction with CB1 and CB2 receptors. This process is a professionals modulation as the endocannabinoid levels enhance through inhibiting the enzymes.

The widespread therapeutic impacts of CBD oil e-liquid are also due to the compound’s ability to influence various receptors across the body.


Both of these compounds have different uses with regard to health. However, both compounds are available for consumption in various forms and ways. CBD vape oil can help to reduce depression and anxiety and also relieve cancer-related symptoms.


  • Stimulation of appetite
  • Muscle relaxation
  • Pain relief
  • Sleep
  • Relaxation


  • Pain relief
  • Ant-anxiety
  • Anti-inflammatory
  • Anti-psychotic
  • Neuroprotection
  • Anti-tumoral

While THC is mainly obtained from smoking cannabis, the best way to experience the potential medicinal value of CBD is through vaping the best CBD oil.

The legality of CBD E-Liquids

This topic bothers many vaping enthusiasts. While most countries and states have stringent regulations on THC and marijuana, the lawfulness of pure cannabidiol is not apparent.

According to a DEA ruling in 2016 publicly declared, all marijuana extracts are classified as Schedule 1 drugs. However, it should be noted that CBD is not explicitly listed under the US Controlled.

Substances Act.

THC and marijuana are prohibited by federal law under the U.S Controlled Substances Act. Although the use of medical marijuana with high levels of THC is allowed in most states, its sale is only permitted if the user presents a recommendation from a licensed physician.

Cannabidiol, on the other hand, is legally available in the United States. However, only the compounds from hemp plants with less than 0.3% THC fit.

CBD products derived from hemp plants like CBD e-liquid, gummies, and patches are legal in the United States where they serve as relaxants and dietary supplements.

Cannabidiol collected from marijuana is illegal unless it comes from medical marijuana or is acquired through a marijuana program by the state.

Frequently Asked Questions

There are some issues that most consumers are usually faced with when looking for CBD e-juices. Here are some of the Frequently Asked Questions about CBD vape oils:

Which is the Best E-Juice with CBD?

Based on the detailed analysis of CBD e-juices in this section, there is no doubt that the products reviewed here are excellent choices for vaping enthusiasts to consider.

However, it’s important to remember that the selection of the CBD e-liquid to buy should depend on the contents of the bottle and the desired experience.

For instance, searching for the best e-cig juice for cloud customers should pay attention to concentration and PV/VG ratio(80/20 fits). Purchase of e-juice with cannabidiol might be challenging, and sampling a few products is a reasonable issue for such struggles.

Where to Buy the Best CBD E-Liquids

Several vendors offer e-juices with CBD for sale both in online and local stores. While all claim to stock the best quality products, some have better outcomes than others. Without knowing the right place to buy CBD e-juices, consumers can quickly become victims of unscrupulous vendors.

In fact, a new consumer can get lost in liquids characteristics and still left with no idea what is the best full spectrum vape juice for big clouds. Online shopping is the way to look for CBD e-liquid for sale, review, and user recommendations.

All brands are in one click distance now, which decides on the product to buy or the vendor to order from more essential.

How many drops of CBD oil do I put in my vape?

Most of the oils come in a dropper bottle and have an instruction for use. Sometimes the total amount of CBD doesn’t specify on the packaging.

A single drop of oil is 0.05 ml which means the 10 ml bottle contains 200 drops and 1,000 mg of CBD, each drop contains 5 mg of CBD. If you want to take 20 mg of CBD, you should take 4 drops. However, it is recommended to consult a doctor before trying oils.

Will vaping CBD make me sleepy?

There is no evidence that cannabidiol makes a person sleepy. CBD compounds can help to relax, calm down the mind and reduce anxiety. It should be taken at least an hour before going to bed to improve falling asleep.

Final Thoughts On The Best CBD Vape Oil

The review is like confessions of experts, manufacturers, and consumers of products. They provide useful insight into what makes the best e-liquid juices that consumers should consider buying.

Making inquiries from vendors before buying CBD e-liquids can also help when it comes to choosing these products. What’s more, new consumers can talk to experienced users about their experiences with specific CBD e juices.

Published: November 2, 2018 Updated: September 28, 2021



Leave a comment

4 comments on “Best CBD Vape Oil of 2022 Review

  • Victor John

    October 12, 2018 at 7:46 am

    Hi Everyone,
    I am looking for CBD products and I wan to use it as soon as possible. So le me know is there any CBD vape user? cause I am not feeling good always I have sleeping problem. I have heard about such things which are giving a lot of relax with amazing benefits.
    Victor John

    • Alexus Heath

      October 29, 2018 at 1:44 pm

      I recently started vaping CDB because of my sleeping, stress, and anxiety problems. It helped me so much. Be careful how much CDB you put in it.

      try looking at hemp bombs.

      I like their products.

  • Michael

    October 1, 2018 at 12:06 pm

    Premium CBD vape e liquid. Has no nicotine no HTC. Can I mix vape juice that have nicotine in them with CBD vape e liquids together in vaper smoke it mix?

  • Robert warren

    August 11, 2018 at 9:43 pm

    Premium CBD vape e liquid. Has no nicotine no HTC. Can I mix vape juice that have nicotine in them with CBD vape e liquids together in vaper smoke it mix.

1st Place 10/10

Empe CBD