Best Diacetyl-Free E-Juices of 2019

Diacetyl is a chemical that occurs in low concentration in coffee, honey, apples, vinegar, and tobacco. It is used by manufacturers to add a buttery taste to products like oil sprays, snack food, margarine and lately e-juices. Heated diacetyl may cause coughing and lead to respiratory sickness. Thus diacetyl-free e-juice flavoring is in high demand among savvy vapers – and for a good reason. E-liquid companies are aware of this and for the most part, have made conscious efforts in reducing or eliminating this chemical. Some manufacturers took this step and started producing superior, safe e-juices that deserve top charts positions.

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Best Diacetyl-Free E-Juices

Check out top e-juices by the most trusted brands.

strawberry shortcake ice cream

#1 VaporFi Strawberry Shortcake Ice Cream

Located in Orange County, California, cosmic vapors strives to provide only the highest quality e-liquids. The process begins in an FDA registered lab, using the latest manufacturing equipment and technology. Their glycerin is “top rated” and extracted from soybeans, making it safe for those with peanut allergies. Most importantly, the quality of their flavorings exceeds food grade by being specially designed for inhalation.

Delicately balanced to provide a blast of strawberry flavor with a creamy ice cream undertone, this delicious all-day vape has been received with almost universal acclaim.


  • 70/30 VG provides a smooth vape with excellent clouds
  • No unpleasant aftertaste Strawberry flavor feels natural and authentic
  • Very mild throat hit
  • Good value at$25.99 per 60ml bottle
  • Detailed ingredients on the packaging


  • Only available in 30ml bottles
  • Strawberry may be overpowering to some
  • Does not work well with some atomizers
  • Sugary flavor is harder on coils
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old fashioned vape juice

#2 Old Fashioned R&R by Motley Brew

Motley Brew advertises itself as “…the company that rocks your vape experience” – and for a good reason. The founders of this company are as passionate and carefree as the people they seek to satisfy.

Frustrated with the flood of substandard e-liquids they claim have been flooding the market, Motley Brew set out to create high quality, premium e-juices that set them apart from the competition.

A combination of bourbon and citrus, this is the perfect vape for people who want to indulge in their favorite cocktail, no matter what the time day. Having won Best in Show for Drinks and Cocktails at the 2015 Vape Summit, Old School R&R carries flavors of whiskey, citrus, and bitters with a slightly sweet undertone. This unforgettable flavor is coming soon on the official manufacturers’ website to satisfy real connoisseurs.


  • 70/30 PG/VG is perfect for sub ohm devices
  • A good mix of tartness and sweetness
  • Available as high as 18mg of nicotine
  • Fitting for both new and experienced vapers
  • Only $5.00 for a 30ml bottle


  • Throat hit can be a bit strong for some
  • Whiskey can be overpowering and almost cigar-like
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grape vape by vape element

#3 FAR Grape by Vape Element

Based in Florida, Element E-Liquid has always strived to create superior products by using only the highest quality ingredients. To keep this tradition going, Element sources its nicotine and other ingredients components from well-recognized companies in the industry.

All of the Element’s products are proudly made in the U.S.A. and adhere to American manufacturing standards and are officially certified to produce e-liquids.

FAR Grape Vape is a medley of ruby red and concord grapes, giving it a taste akin to the grape soda so beloved by soda drinkers everywhere. With a solid flavor that is not too overpowering, FAR Grape Vape is the perfect diacetyl-free e-juice for fruit and drink lovers alike.


  • 75/25 VG/PG content makes it even smoother than many liquids
  • An appropriate choice for cloud-chasers
  • Available in 20ml and 100ml bottles
  • Creative packaging design
  • Very affordable at only $36.99 for 100ml


  • Not ideal for those who do not like fruits or grapes
  • Only available up to 6mg of nicotine
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pear almond e-liquid

#4 Ripe Vapes Pear Almond E-Liquid

Ripe Vapes aims to brand itself as being “…more like a wine tasting experience than a pop culture fad,” seeking to create this experience through its labeling and unique flavors.

This award-winning company has a massive share of recognition under its belt. Having won Best in Show Overall at Vape Summit One, Best Tobacco Product from Vape Summit Two, Best Tobacco E-Liquid from Vape Jam UK 2016 and the 2014 Spinfuel Choice Award, Ripe Vapes’ reputation speaks for itself.

The company is proud to be diacetyl-free while obtaining its nicotine, glycerine, and flavorings from only the highest quality, reliable sources.
Created with the fine dessert connoisseur in mind, Pear Almond is a mix of European pastries and mild fruit flavor. The primary taste of marzipan takes the spotlight, with small (but noticeable) hints of fresh pear. Suffice to say, this is not a generic dessert flavor.


  • 75/25 VG/PG blend is perfect for sub-ohm devices
  • Unique presentation
  • Offers both 30 and 60ml option
  • Lab test results available on their website
  • Available up to 18mg of nicotine, making it perfect for new vapers
  • Does an excellent job of balancing the marzipan and pear flavors
  • Acceptably priced at $19.95 for 60ml


  • Pear flavor does not taste authentic
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remixed vape juices

#5 Remixed Sampler Pack by Motley Brew

Another affordable offer from one of the award-winning diacetyl-free e-juice brands, this sampler pack has something for everyone. Crumb DMC is a dessert-lover’s dream. Right from the beginning, vapers will taste the sweet tartness of red apple, followed by a subtle aroma of crumb cake. It is perfect for those looking to enjoy apple crumble at any time.

Another pastry flavor, The Drop is a combination of key lime cookie and blueberry with a hint of vanilla. This balanced blend of dessert and fruit flavors makes it the perfect choice for pastry and fruit fans alike.

A sharp left turn from its dessert counterparts, Bubble Pop, comes in strong with the powerful taste of strawberry bubblegum. Kiwi and watermelon take over upon exit, providing a unique, candy flavor that only Motley Brew can provide.


  • 70/30 PG/VG adds smoothness, especially for the pastry flavors
  • Plenty of variety Nicotine options as high as 12mg
  • Only $15.00 for three 30ml bottles


  • Only available in 30ml
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Health Benefits of diacetyl-free E-Liquid

According to the Centers for Disease Control (CDC), diacetyl is best known for its use in popcorn flavorings (but has since found itself in many e-liquids). It was eventually associated with lung damage, resulting in decreased respiratory function. Animal studies by the CDC also showed severe lung impact following diacetyl exposure. Frequent vapers greatly significantly reduce potential respiratory harm by avoiding this substance.

Diacetyl is safe to ingest, but research shows it is hazardous when inhaled. This chemical is not a necessary component in e-liquids, so always research the product in order to prevent potential lung damage.

Where Can Consumers Find diacetyl-free E-Juice Vendors?

While there is no directory or online compilation of companies that avoid diacetyl, they are easy to identify nonetheless. E-liquid manufacturers know this chemical’s dangers and make efforts to self-regulate. They often advertise that their products as diacetyl-free and post-third-party lab tests on their websites as proof.

No ID Diacetyl (μg/ml)
1 Grandmaster ND < 5
2 Gambit 16.0
3 Castle Long ND < 5
4 Sixty-Four ND < 5
5 Lucena 24.8
6 Fifth Rank ND < 5
7 Absolute Pin 8.4
8 Perpetual Check 130.8
9 Bowden’s Mate ND < 5
10 Queenside ND < 5


The lab test results from several e-juices shows that diacetyl has been found in varying degrees, depending on the flavor.

The letters “ND” stand for “non-detect,” implying that the amounts were too insignificant for the equipment to find any diacetyl. This legend is universally used in third-party lab analyses, making the results simple to read and allowing consumers to identify diacetyl-free e-liquid easily.

Lab tests published by Harvard University in June 2016 found that diacetyl was most prominent in tobacco and menthol flavored e-liquids; however, the e-cigarette industry has evolved considerably year over year. While menthol and tobacco are likely culprits for diacetyl, they do not universally contain it.

Quick Facts About Diacetyl

  • Although used in artificial flavorings, diacetyl is created naturally through yeast fermentation.
  • In addition to buttery flavors, diacetyl is used in some Chardonnay wines and a wide variety of fruit flavors consumed on a daily basis.
  • Diacetyl gained infamy when it was linked to a condition called bronchiolitis obliterans – colloquially referred to as “popcorn lung” due to the harmful effects of its inhalation popcorn factories that lacked ventilation.

Diacetyl – like many substances – is both benign and dangerous. Although safely used for years as a food flavoring, it is clear that the substance is unsafe for inhalation.

Fortunately, there are thousands of brands and flavors available that not only avoid diacetyl but also use very high quality, reputable ingredients. The aura of transparency and responsibility in the e-liquid market is truly notable, so vapers everywhere should support and promote diacetyl-free e-liquid brands.


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Posted by
Thanush Poulsen

Being a regular Sweden student, I discovered innovative ways of living healthier. And with my very first e-cigarette, I’ve got obsessed with all things digital. So vaping collided my interests in electronics, science, and health. I enjoy bringing people into the world of vaping through my reviews, guides, and best-of lists.