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VaporFi Pure Grape E-Liquid
VaporFi Pure Grape E-Liquid
10/10 icon-question
  • Available in two nicotine strengths (3mg, 6mg)
  • Available in a single VG/PG ratio, 70/30
  • Available in a single 60ml bottle

The VaporFi Pure Grape e-juice delivers on its promise and offers users a classic, mouth-watering grape flavor with every inhale and exha...

Virginia Burley
Virginia Burley vape juice
  • 70/30 and 60/40 VG/PG ratios available
  • Made from US-grown tobacco
  • Made and bottled in the US
Valerian Root Natural Relaxant and Sleep Aid
Valerian Root Natural Relaxant and Sleep Aid
  • 50/50 VG/PG Ratio
  • 10 Percent Valerian/Sage Extract Ratio
  • Child-Proof Cap

Best Diacetyl-Free Vape Juices

#1 VaporFi Pure Grape E-Liquid

The Purest, Juiciest Grape Flavor of All

10/10 icon-question Review score

The VaporFi Pure Grape e-juice delivers on its promise and offers users a classic, mouth-watering grape flavor with every inhale and exhale. This diacetyl-free e-juice consists of only one flavor profile. It succeeds in creating an unforgettable vaping experience with the taste of freshly-picked grapes in every drop of vapor.


  • Smooth, great-tasting flavor
  • Great aftertaste
  • A touch of sweetness
  • Good throat hit


  • No other flavors present

#2 Virginia Burley

Diacetyl-Free E-Liquid

9.5/10 icon-question Review score

Tobacco vaping liquids are great for former cigarette smokers. They allow them to continue using their favorite flavors without having to use cigarettes or cigars. This flavor uses natural tobacco with a hint of menthol to create a well-balanced taste. Additionally, the liquid is filtered and left to age for several months to be as flavorful as possible.


  • Outstanding flavor
  • Different VG/PG ratios
  • Compatible with MTL pod mods and DTL tanks


  • No 50/50 VG/PG

#3 Valerian Root Natural Relaxant and Sleep Aid

Diacetyl-Free E-Juice

9/10 icon-question Review score

Valerian root is a natural sleep aid and stress reducer that has been used for centuries to treat nervous system disorders and insomnia.

The root produces isovaleric and valerenic acid. These are compounds that cause calming and sedative effects. Now, these compounds are present in this vape oil from ePuffer. A hit from this e-liquid will help the user relax at the end of the day and fall asleep faster.


  • Relaxing and calming effect
  • Good taste
  • No nicotine or CBD Good taste


  • Expensive

#4 Midnight Pleasure E-liquid

A Crisp, Flavorful E-Juice

9.5/10 icon-question Review score

The Midnight Pleasure e-liquid promises to seduce vapers with its slow reveal of tastes that promise to excite and delight. The shisha-inspired e-juice captures several bold flavors in its vapor cloud as it introduces several tastes into the cloud.

Many users report noticing new flavors only after a few days of using the e-juice. The first that stands out is menthol, but users will soon notice that the cloud contains hints of delectable, fruity tastes. It rounds out the overall experience of the vape that promises a bevy of new flavors.


  • Great after-dinner vape
  • 60/40 PG/VG ratio (flavoring 10%)
  • 0mg, 6mg, 12mg, 24mg


  • Might be too sweet for some

#5 Black Note Menthol Blend

Classic Menthol With No Added Chemicals

9/10 icon-question Review score

The Black Note Menthol Blend e-juice is made with all-natural ingredients. It contains no added flavors, colors, or chemicals like diacetyl. Even the nicotine in Black Note products is extracted from real tobacco leaves. So the product is as pure as it can get. The brand’s take on menthol is a winning combination of their commitment to quality as the tobacco and menthol tastes blend masterfully and release a refreshing blast of mint at the end.


  • Superb flavor profile
  • Great evening or after-dinner vape
  • Smooth aftertaste
  • Good throat hit


  • No other noticeable flavors

#6 Sadboy Punch Berry

A Sweet and Sour Mixture

8.5/10 icon-question Review score

The Sadboy Punch Berry has the most exciting name because it features the most exciting flavor combinations. The e-juice has a fruit medley that features several berries like raspberries and blueberries while also adding a touch of citrus. The vape starts with those berries’ sweet, juicy tastes and ends with a sucker punch of lemon to finish off with a bang.


  • Good combination of tastes (sweet and sour)
  • Good vapor production
  • Refreshing flavor
  • Good throat hit


  • Too sour at the end

#7 I Love Salts Classic Menthol

A Pure Menthol Experience

8/10 icon-question Review score

Mad Hatter’s I Love Salts Classic Menthol e-juice contains no added ingredients, flavors, or additives. Instead, the e-juice is an expression of pure minty joyfulness as users inhale a medium cool blast of menthol and hold it until they can hold it no longer. In addition, the e-juice features a long-lasting aftertaste like all of your favorite menthol products do, from chewing gum to iced tea.


  • Authentic menthol flavor
  • Great all-day vape
  • Smooth throat hit
  • Good for low-wattage devices


  • No other noticeable flavors

Category Name Rating Price
Safest Vape Juice VaporFi Pure Grape E-Liquid 10 $16.95
Best Diacetyl-Free Vape Juice Kai's Virgin Vapor Plum Crazy 9,5 $39,99
Organic Vape Juice Virginia Burley 9 $21,95
Best Natural Diacetyl-Free Vape Juice Valerian Root Natural Relaxant and Sleep Aid 8,5 $34,95
Best Diacetyl-Free Vape Juice Midnight Pleasure E-liquid 8,5 $15.95
Best Menthol Vape Juice Black Note Menthol Blend 8 $33.00
Best Vape Juice Flavor Sadboy Punch Berry 7.5 $11.99
Best Cheap Vape Juice I Love Salts Classic Menthol 7 $9.79

What is Diacetyl?

Diacetyl is a naturally occurring yeast often added to dairy products to enhance flavor. Diacetyl is classified by the FDA as generally recognized as a safe food additive. It has been found in consumer food products as wide-ranging as cheese, milk, and yoghurt. It has also been used as a food coloring for confectionery products like caramel or coffee-flavoured desserts.

The compound is safe to ingest. In the late 2000s, however, it was discovered that inhalation of the aerosol form of diacetyl led to scarring in the lungs and airways of several workers at a manufacturing plant that made microwave popcorn. The illness popularly referred to as “popcorn lung” is irreversible. It has subsequently been found in other food manufacturing plants that use diacetyl.

The term “popcorn lung” was coined to describe incurable lung disease. It affected workers at a factory that made microwave popcorn. The disease is officially known as bronchiolitis obliterans. Because of this, diacetyl has been removed as an ingredient from all e-juices. However, users should still look for e-juice without diacetyl on the ingredient list.

Health Benefits of Diacetyl-Free E-Liquid

According to the Centers for Disease Control (CDC), diacetyl is best known for its use in popcorn flavorings. It was eventually associated with lung damage, resulting in decreased respiratory function. Animal studies by the CDC also showed severe lung impact following diacetyl exposure. Therefore, frequent vapers significantly reduce potential respiratory harm by avoiding this substance.

Diacetyl in vape juice is safe to ingest, but the research shows it is hazardous when inhaled. This chemical is not a necessary component in e-liquids, so always research the product to prevent potential lung damage.

What Does Diacetyl Do to the Lungs?

In high enough amounts, diacetyl can cause bronchiolitis obliterans. This disease can cause a chronic dry cough, wheezing, and fatigue. However, it is unknown whether diacetyl in vape juice causes bronchial obliterans because it has to be inhaled in very high concentrations.

What Is the Healthiest Way to Vape?

The long-term health effects of vaping are unknown, so it is impossible to say whether there is a healthy way to do it.

How To Find Out if Diacetyl Is In Your E-Juice?

Diacetyl was an ingredient in some early e-juices. But it has been removed from all commercially available e-liquids. However, because of its versatility and similarity to various flavor profiles (sweet, dessert, coffee), diacetyl was thought to be a natural addition to e-juices to improve their flavors.

But the makers of those e-liquids did not think that inhaling the substance would be harmful until the evidence proved otherwise. As diacetyl has become a banned ingredient, no reputable e-juice company includes it in its products. Instead, users can check an ingredient list, if one is available, to make sure there is no diacetyl present.

Some manufacturers mention that their vape liquids are diacetyl-free, while others are not so transparent. But as the vape industry has come under much scrutiny over the past few years, any e-juice maker that wants to receive a PMTA (premarket tobacco approval) from the FDA would be wise to not include the substance in any of their e-juices.

Where Can Consumers Find Diacetyl-Free E-Juice Vendors?

The lab test results from several e-juices show that diacetyl has been found in varying degrees, depending on the flavor.

The letters “ND” stand for “non-detect,” implying that the amounts were too insignificant for the equipment to find any diacetyl. This legend is used in third-party lab analyses, making the results simple to read. Also, it allows consumers to identify diacetyl-free vape juice easily.

Lab tests published by Harvard University in June 2016 found that diacetyl was most prominent in tobacco and menthol-flavored e-liquids. However, the e-cigarette industry has evolved considerably year over year. While menthol and tobacco are likely culprits for diacetyl, they do not universally contain it.


Diacetyl caused panic in many vaping circles when it was discovered that many e-juice manufacturers unwittingly added it to their products. After the public outcry, the industry took action. Manufacturers pledged to remove the substance from all their e-juices. Instead, they use other, safer flavorings for their butter-based flavors. But users should still be vigilant and make sure that they buy e-juice only from reputable manufacturers and retailers. Then they can avoid any possible, life-changing consequences.

Published: July 10, 2018 Updated: September 12, 2022



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VaporFi Pure Grape E-Liquid